A quality by design (QbD) twin—Screw extrusion wet granulation approach for processing water insoluble drugs
نویسندگان
چکیده
منابع مشابه
Aspects of Screw Design for Wet Granulation Extrusion
This paper discusses our preliminary trials examining the particle size and particle shape of granules produced by different screw elements in a co-rotating twin-screw extruder. In general, conveying elements did not provide the necessary consolidation to allow large particles to grow in significant quantity, whereas the different mixing elements led to the large particles desired for tablettin...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2017
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2017.05.020